欧宝体育app
请解决为您讲授什么样是KRAS?RAS是GTPase原癌遗传基因氏族人员,具有3个密切联系相应的的RAS亚型,HRAS,KRAS and NRAS。RAS is a family of GTPase proto-oncogenes, comprising three closely related RAS isoforms:HRAS,KRAS and NRAS.在每个RAS亚型中,KRAS突然变化速度更高,KRAS突然变化分类于胰腺癌,癌症和结阑尾癌。KRAS gene is a proto-oncogene that encodes a GTP/GDP-binding protein, that belongs to the GTPase RAS family.KRASdna是商品编号GTP/GDP切合血清的原癌dna,是GTPase RAS家簇。KRAS血清作原子触点开关,在GDP切合的无亲水性睡眠的状态和GTP切合的亲水性睡眠的状态之間反复。KRAS血清都进行与GTP和GDP切合,在无亲水性原子和亲水性状态之間换为。The KRAS protein acts as molecular switches that cycle between a GDP-bound inactive state and a GTP-bound active state. KRAS protein switches between an inactive to an active form via binding to GTP and GDP respectively。